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The science behind anabolic steroids
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A class of synthetic medications known as anabolic steroids. They mimic the actions of testosterone, the male sex hormone. Medically, it is to treat some hormone problems in men, delayed puberty, and muscle loss from some diseases.
Anabolic steroids cause muscle cells to produce more muscular protein, which results in larger muscles.
Additionally, they bind to glucocorticoid receptors, preventing the breakdown of muscle.
Let's look at the history of steroid and when was it firstly used.
When English physician William Withering utilized digitalis, a substance taken from the leaves of the common foxglove (Digitalis purpurea), to treat edema in the 18th century, it was the first time that steroids were used medically.
In the early 19th century, studies on steroids began with investigations into the unsaponifiable components of animal fat and bile, leading to the isolation of cholesterol and bile acids.
It wasn't until the 20th century that the complex steroid structure was fully understood, thanks to advancements in chemical theory and techniques. German chemists like Adolf Windaus and Heinrich Wieland played crucial roles in elucidating the structures of cholesterol, sterols, and bile acids.
This era saw the emergence of a thriving steroid pharmaceutical industry and a deepened understanding of steroid biochemistry, including metabolic pathways and hormonal roles in mammals and other organisms.
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